Berberine is a dietary supplement, the principal bioactive ingredient various plants such as Berberis vulgaris (barberry) and Berberis Aristata and in common traditional Chinese medicinal herbs (also named ‘Huang Lian’ in Chinese) traditionally used to address various health challenges. It comes from the roots, stems, and bark of various plants. According to inscriptions found on clay tablets in the library of the Assyrian Emperor Ashurbanipal, one of the earliest use of Berberine containing fruits goes back to 650 BCE. These tablets refer to the purifying effects of Berberine-containing fruits. In Ayurvedic medicine, Berberine was used for example for ‘open the mind’. The plant use in Chinese medicine dates back over 3000 years, and it’s use in the European countries has a similarly long history.
Today, Berberine is widely used in Asian countries (mainly in China) due to its good clinical and safety profile. In US, FDA considers Berberine safe for human use.
In line with the traditional use, and the recent findings, currently Berberine is considered:
- Good for liver* [EFSA ID 3989]
- Good for blood glucose* [EFSA ID 4363]
- Good for cholesterol* [EFSA ID 3272]
Therefore, there are indeed good reasons why Berberine is such a prominent herb. To further maximize the absorption of Berberine we recommend its combination with another of our products, Milk Thistle Pure.
While the academic and clinical findings related to its potential are numerous (more than 8400 published studies listed on PubMed) and many are often outstanding, supporting its traditional use, inline with the European regulation, these findings cannot be addressed here.
*The statements in this section have not been evaluated by the FDA or EFSA, but they are under review at EFSA.
MCS Formulas provides high Quality and Purity Berberine …
Our Berberine capsules include high purity Indian Berberine (>97% purity) manufactured by one of the highest quality manufacturer, i.e. Sabinsa Corporation.
…. formulated in an outstanding absorption promoting formula
However, we did not stop here. Instead, in order to maximize the absorption of Berberine, we have designed a Berberine formula based on the pro liposomal technology LongLifeLipoTech™.
Indeed, a major approach known to maximize bio-availability of natural compounds are phospholipid-based formulations. These are available commercially and known as liposomal formulations. They come as liquid emulsions or solid formulations promoting the formation of liposomal structures (bubble-like structures surrounded by a fat-based layer) that can encapsulate the active ingredients such as Berberine compounds. This phospholipid layer is similar to the cell walls in our body. As a result, liposomes are well received by the body and absorbed in higher quantities by the body, to reach the blood stream.
While liposomal formulations are a great way to deliver increased amount of supplements and drugs to the blood stream, when turning these into liquid products, it leads to various disadvantages for the users. Liposomal products are liquid, heavy and difficult to carry. They have often bad taste. Making their taste better may come with various undesired additives. And typically they have short shelf life, even shorter after the bottle is open. Furthermore, liquid liposomal products need to stay stored at low temperature.
In contrast to the liquid liposomal supplements, liposomal promoting formulations as dry powder in capsules have no taste, they are easy to carry, and they can be stored at room temperature with a long shelf life. The quality is therefore even better since the product is more stable.
Furthermore, phospholipids can be negatively or positively charged leading to a lower absorption and time to circulate in the blood stream, compared to neutrally charged liposomes. In order to address this and further maximize the absorption, our Pro Liposomal formula includes LongLifeLipoTech™
LongLifeLipoTech™ is a pro liposomal technology that includes a proprietary blend of Phospholipids and Chitosan designed with the intention to promote the formation of neutrally charged liposomes. Indeed, it is known that Chitosan naturally binds to charged phospholipids to form neutrally charged liposomes. This is how, LongLifeLipoTech™ pro liposomal blend, supports the formation of liposomes that can have a better biocompatibility (improved absorption and a longer circulating time in the blood stream) compared to formulas based on phospholipids alone.
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